| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Sebastián de Pastrana | |
| Bishop of Paraguay | |
| Church: | Catholic Church |
| Diocese: | Diocese of Paraguay |
| Term: | 1693–1700 |
| Predecessor: | Faustino Casas Hernández |
| Successor: | Pedro Díaz de Durana |
| Consecration: | 1697 |
| Consecrated By: | Melchor de Liñán y Cisneros |
| Birth Date: | 1633 |
| Birth Place: | Lima, Peru |
| Death Date: | 4 November 1700 (age 67) |
| Death Place: | Asunción, Paraguay |
Sebastián de Pastrana, O. de M. (1633–1700) was a Roman Catholic prelate who was Bishop of Paraguay (1693–1700).[1]
Sebastián de Pastrana was born in Lima, Peru, in 1633 and ordained a priest in the Order of the Blessed Virgin Mary of Mercy.[2] On 24 August 1693, he was appointed during the papacy of Pope Innocent XII as Bishop of Paraguay. In 1697, he was consecrated bishop by Melchor de Liñán y Cisneros, Archbishop of Lima. He was Bishop of Paraguay until his death on 4 November 1700.