| Sebastián Brusco | |
| Fullname: | José Sebastián Brusco |
| Height: | 1.850NaN0 |
| Birth Date: | 8 October 1974 |
| Years1: | 1993–1996 |
| Years2: | 1997–1998 |
| Years3: | 1999 |
| Years4: | 1999–2000 |
| Years5: | 2000–2001 |
| Years6: | 2001–2002 |
| Years7: | 2002–2003 |
| Years8: | 2003–2005 |
| Years9: | 2005–2006 |
| Years10: | 2006–2008 |
| Years11: | 2008–2009 |
| Caps1: | 71 |
| Caps2: | 41 |
| Caps3: | 4 |
| Caps4: | 26 |
| Caps5: | 36 |
| Caps6: | 31 |
| Caps7: | 17 |
| Caps8: | 64 |
| Caps9: | 32 |
| Caps10: | 63 |
| Caps11: | 32 |
| Goals1: | 7 |
| Goals2: | 6 |
| Goals3: | 0 |
| Goals4: | 9 |
| Goals5: | 2 |
| Goals6: | 5 |
| Goals7: | 0 |
| Goals8: | 2 |
| Goals9: | 1 |
| Goals10: | 15 |
| Goals11: | 0 |
José Sebastián Brusco (born October 8, 1974) is a formed Argentine football defender.
Brusco was born in Villa María, Córdoba. He started his professional playing career in 1993 with Belgrano de Córdoba. In 1996, he joined Racing Club de Avellaneda
In 1999, he had a short spell with Toros Neza in Mexico before returning to Argentina to play for Godoy Cruz and then Instituto de Córdoba in the 2nd division.
In 2001 Brusco returned to Belgrano de Córdoba before moving to Gimnasia y Esgrima de La Plata. In 2003, he returned for a 3rd spell with Belgrano de Córdoba where he stayed until 2005.
In 2005 Brusco joined Bolivian side Blooming and won the Apertura tournament that same year. The following season he was signed by San Martín de San Juan with which later gained promotion to the Argentine Primera after defeating Huracán on a 3-2 aggregated. After a couple of years with San Martín, Brusco changed colors by joining Independiente Rivadavia.