Sean Eddy Explained

Sean Eddy
Birth Name:Sean Roberts Eddy
Fields:Computational Genome Analysis
Doctoral Advisor:Larry Gold
Thesis Title:Introns in the T-even bacteriophages
Thesis Url:http://search.proquest.com/docview/303935681/
Thesis Year:1991
Academic Advisors:John Sulston
Richard Durbin
Prizes:Ben Franklin award (2007)

Sean Roberts Eddy is Professor of Molecular & Cellular Biology and of Applied Mathematics at Harvard University. Previously he was based at the Janelia Research Campus from 2006 to 2015[1] [2] in Virginia. His research interests are in bioinformatics, computational biology and biological sequence analysis.[3] [4] [5] projects include the use of Hidden Markov models[6] [7] in HMMER, Infernal[8] Pfam and Rfam.[9] [10] [11]

Education

Eddy graduated June, 1982 from Marion Center Area High School, Marion Center, Pennsylvania. He then completed a Bachelor of Science in Biology at California Institute of Technology in 1986,[12] followed by a Doctor of Philosophy in molecular biology at the University of Colorado under the supervision of Larry Gold in 1991 studying the T4 phage.[13] [14] [15]

Career

From 1992 to 1995 he was a postdoctoral research fellow at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge UK working with John Sulston and Richard Durbin. From 1995 to 2007 he worked at Washington University School of Medicine and has been working for the Howard Hughes Medical Institute since 2000.

Awards and honours

In 2007, Sean was the winner of the Benjamin Franklin Award in Bioinformatics for contributions to Open Access in the Life Sciences.[16]

In 2022, Eddy was elected as a Fellow of the International Society for Computational Biology.[17]

Notes and References

  1. Web site: HHMI Scientist Bio: Sean R. Eddy, Ph.D. . Anon . 2012 . 2012-06-16 . https://web.archive.org/web/20120616073439/http://www.hhmi.org/research/groupleaders/eddy_bio.html . dead .
  2. Kaplan . Karen . A roll of the dice: Sean Eddy has his dream job. 10.1038/nj7373-433a . . 479 . 7373 . 433–435 . 2011 . 22106470. free .
  3. Rivas . E. . Lang . R. . Eddy . S. R. . Sean Eddy. 10.1261/rna.030049.111 . A range of complex probabilistic models for RNA secondary structure prediction that includes the nearest-neighbor model and more . RNA . 18 . 2 . 193–212 . 2011 . 22194308 . 3264907 .
  4. E. S.. Lander. Eric Lander. Linton . M. . Birren . B. . Nusbaum . C. . Zody . C.. Baldwin . J. . Devon . K. . Dewar . K. . Doyle . M. . Fitzhugh . W. . Funke . R. . Gage . D. . Harris . K. . Heaford . A. . Howland . J. . Kann . L. . Lehoczky . J. . Levine . R. . McEwan . P. . McKernan . K. . Meldrim . J. . Mesirov . J. P. . Miranda . C. . Morris . W. . Naylor . J. . Raymond . C. . Rosetti . M. . Santos . R. . Sheridan . A. . Sougnez . C. . 29. Initial sequencing and analysis of the human genome . Nature . 409 . 6822 . 860–921 . Feb 2001 . 0028-0836 . 11237011 . 10.1038/35057062. 2001Natur.409..860L. free .
  5. Web site: Sean Eddy's homepage. selab.janelia.org. dead. https://web.archive.org/web/20101204101639/http://selab.janelia.org/people/eddys/. 2010-12-04.
  6. Eddy . S. R. . Sean Eddy. What is a hidden Markov model? . 10.1038/nbt1004-1315 . . 22 . 10 . 1315–1316 . 2004 . 15470472. free .
  7. Eddy . S. . Sean Eddy. Profile hidden Markov models . Bioinformatics . 14 . 9 . 755–763 . 1998 . 9918945 . 10.1093/bioinformatics/14.9.755. free .
  8. Web site: Sean Eddy's blog. cryptogenomicon.org.
  9. Eddy . S. R. . Sean Eddy. The C-value paradox, junk DNA and ENCODE . 10.1016/j.cub.2012.10.002 . Current Biology . 22 . 21 . R898–R899 . 2012 . 23137679. free .
  10. , GenomeTV
  11. , 2013-07-20
  12. Web site: Sean Eddy CV . selab.janelia.org . dead . https://web.archive.org/web/20120309235306/http://selab.janelia.org/people/eddys/cv.pdf . 2012-03-09 .
  13. PhD . Sean Roberts. Eddy . Introns in the T-even bacteriophages . University of Colorado . 1991 . 28253022. .
  14. Eddy . S. R. . Sean Eddy. Gold . L. . The phage T4 nrdB intron: A deletion mutant of a version found in the wild . Genes & Development . 5 . 6 . 1032–1041 . 1991 . 2044951 . 10.1101/gad.5.6.1032. free .
  15. Tuerk . C. . Eddy . S. . Sean Eddy. Parma . D. . Gold . L. . Autogenous translational operator recognized by bacteriophage T4 DNA polymerase . 10.1016/S0022-2836(05)80261-X . . 213 . 4 . 749–761 . 1990 . 2359122 .
  16. Web site: BioMed Central Blog: Sean Eddy wins open access award . blogs.openaccesscentral.com . Anon . 2007 . dead . https://web.archive.org/web/20110607081718/http://blogs.openaccesscentral.com/blogs/bmcblog/entry/sean_eddy_wins_open_access . 2011-06-07 .
  17. Web site: April 28, 2022: ISCB Congratulates and Introduces the 2022 Class of Fellows! . www.iscb.org . 17 June 2022.

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