Scutellaria ocmulgee, commonly known as Ocmulgee skullcap, is a species of herbaceous perennial plant found only in the Savannah River (South Carolina and Georgia) and the Ocmulgee River (Georgia) watersheds.
Ocmulgee skullcap was first described as a new species in 1898 based on a specimen collected along the Ocmulgee River in Bibb County, Georgia.