Scutelarin Explained

Scutelarin
Ec Number:3.4.21.60
Cas Number:93389-45-8

Scutelarin (taipan activator, Oxyuranus scutellatus prothrombin-activating proteinase) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Selective cleavage of Arg-Thr and Arg-Ile in prothrombin to form thrombin and two inactive fragments

This enzyme is isolated from the venom of the Taipan snake (Oxyuranus scutellatus).

Notes and References

  1. Walker FJ, Owen WG, Esmon CT . Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom) . Biochemistry . 19 . 5 . 1020–3 . March 1980 . 6986908 . 10.1021/bi00546a029 .
  2. Speijer H, Govers-Riemslag JW, Zwaal RF, Rosing J . Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake) . The Journal of Biological Chemistry . 261 . 28 . 13258–67 . October 1986 . 3531198 .

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