Scott D. Tanner Explained

Scott Tanner is a Canadian scientist, inventor,[1] [2] and entrepreneur.[3] His areas of expertise include mass spectroscopy, especially inductively coupled plasma mass spectrometry (ICP-MS), and mass cytometry.

Scott is best known for his work on the fundamentals of Inductively Coupled Plasma Mass Spectrometry,[4] for the invention of mass cytometry,[5] and co-founding (with Dmitry Bandura, Vladimir Baranov and Olga Ornatsky) DVS Sciences in 2004,(acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022[6]) the company that first commercialized the instrument and reagents of mass cytometry.

Early life and education

Scott was born and raised in St. Catharines, Ontario Canada. He bought his first chemistry set, from his brother, at age 6. Through his early teenage years, he was provided with laboratory space at Brock University, under the guidance of Dr. E.A. Cherniak and Dr. F.P. Koffyberg, where he attempted to replicate Geiger–Marsden experiments also known as Rutherford’s experiment (scattering of alpha particles by gold foil) using various home-built instruments, including cloud chambers.[7] [8]

Scott graduated with a BSC in Chemistry from York University in 1976. During his undergraduate years, he became a nationally ranked gymnast.[9] An injury at the Olympic trials ended his competitive gymnastics career, and he took up marathon running during graduate school (best time 2:47:13). He received a Doctor of Philosophy (Chemistry) from York University in 1980, having studied ion-molecule reaction kinetics and flame ion chemistry with Drs. D.K Bohme and J.M. Goodings.

Biography

Dr. Tanner joined SCIEX, which later became MDS SCIEX, in 1980 as a research scientist. He became Principal Scientist in 2000. In his 25 years at SCIEX, Dr. Tanner developed and helped to commercialize a string of Mass Spectrometry products.

Scott published over 74 peer-reviewed scientific articles, and holds 22 US patents[10] (with corresponding filings in other countries), including 13 patents on Mass Cytometry technology

Scott was a co-founder of DVS Sciences and, as the President and CEO, saw the company through the development and commercial launch of its first products.

The products that DVS Sciences brought to the global market were originally developed at the University of Toronto where Dr. Tanner was a Professor in the Institute of Biomaterials and Biomedical Engineering and then in Chemistry.

Career

Books

Research

Awards and honors

Publications

Scott has published more than 75 peer-reviewed articles.
The 13 most cited (more than 200 citations each) include:

A more complete listing of his publications can be found on Google Scholar

External links

Notes and References

  1. Web site: Patents by Inventor Scott D. Tanner . Justia.com.
  2. Web site: Scott D. Taner Inventions . Patentguru.com.
  3. Web site: Co-Founder of DVS Sciences . MaRSdd.com . 2011.
  4. Book: D. J. Douglas . S.D. Tanner . Montaser . Akbar . Fundamental Considerations in ICP-MS . Inductively Coupled Plasma Mass Spectrometry . 1998 . Wiley-VCH . New York . 978-0-471-18620-5 . 615–679 .
  5. Web site: US Patent 7,135,296 . Google Patents . 2000-12-28. 6 December 2022.
  6. Web site: Fluidigm Renamed to Stanard BioTools . Globenewswirel . 9 December 2022 . 2022-04-04.
  7. Web site: Scott Tanner Biography . StemSpecs . Nov 2005. https://web.archive.org/web/20090704095405/http://www.stemspec.ca/Project/History/pdf/newsletter_november.pdf . 2009-07-04 .
  8. Ben Merison . Interview: Raising the Bar . Highlights in Chemical Technology . August 6, 2009 . 2009 . 9 . T65–T72 . https://web.archive.org/web/20121024130218/http://www.rsc.org/Publishing/ChemTech/Volume/2009/09/tanner_interview.asp . 2012-10-24 .
  9. Atonic Spectrometry Viewpoint: Scott Tanner . Journal of Analytical Atomic Spectrometry . January 1995 . 10 . 1 .
  10. Web site: Scott D. Tanner Patents . Google Patents . 6 December 2022.
  11. Web site: President - DVS Sciences . 2009. https://web.archive.org/web/20090619085858/http://www.dvssciences.com/bio.html . 2009-06-19 .
  12. Book: Holland . J. Grenville . Tanner . Scott D. . Plasma Source Mass Spectrometry: Applications and Emerging Technologies . 4 August 2003 . Royal Society of Chemistry . 0854046038 . en.
  13. Book: Holland . J. Grenville . Tanner . Scott D. . Plasma Source Mass Spectrometry : The New Millennium . 2001 . Royal Society of Chemistry . Cambridge . 0854048952 .
  14. Book: Holland . Grenville . Tanner . Scott D. Tanner . Plasma Source Mass Spectrometry: New Developments and Applications . 23 July 1999 . Royal Society of Chemistry . Cambridge, UK . 0854047492 .
  15. Book: Holland . Grenville . Tanner . Scott D. . Plasma Source Mass Spectrometry : Developments and Applications . 1997 . Royal Society of Chemistry . Cambridge . 0854047271 .
  16. Book: T. Sakuma . N. Gurprasad . S.D. Tanner . A. Ngo . W.R. Davidson . H.A. McLeod . B.P-Y Lau . J.J. Ryan . Keith . L.H. . Rappe . C. . Choudhary . G. . Chlorinated Dioxins and Dibenzofurans in the Total Environment II . 139 . 1985 . The Application of Rapid Gas Chromatographic Tandem Mass Spectrometry in the Analysis of Complex Samples for Chlorinated Dioxins and Furans . 21212149M .
  17. Book: The Instantaneous Detection of Explosives by Tandem Mass Spectrometry, S.D. Tanner, W.R. Davidson and J.E. Fulford . 1983 . US Dept of Justice . Quantico, Virginia .
  18. The Use of a Commercially Available Atmospheric Pressure Chemical Ionization Tandem Quadrupole Mass Spectrometer for the Direct Detection of Chemical Agents and Simulants, B.A. Petersen, S.D. Tanner, J.E. Fulford, B.I. Shushan and W.R. Davidson . Proc.of the 1985 Sci. Conf. On Chem. Defence Research, CRDC-SP-86007 . 1986 . 15 . USAAMCC . Aberdeen Proving Ground,Maryland.
  19. E.R. Denoyer . D. Jacques . E. Debrah . S.D. Tanner . Determination of Trace Elements in Uranium: Practical Benefits of a New ICP-MS Lens System . Atomic Spectroscopy. . 1995 . 16 . 1.
  20. Vladimir I. Baranov . Scott D. Tanner . A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). I. The RF-Field Energy Contribution in Thermodynamics of Ion-Molecule Reactions . Journal of Analytical Atomic Spectrometry . 1999 . 14 . 8 . 1133–1142 . 10.1039/a809889a .
  21. S.D. Tanner . V.I. Baranov . A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). II. Reduction of Interferences Produced Within the Cell . Journal of the American Society for Mass Spectrometry . November 1999 . 10 . 11 . 1083–1094 . 10.1016/S1044-0305(99)00081-1 . 93608392 .
  22. Scott D. Tanner . Vladimir I. Baranov . Uwe Vollkopf . A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). III. Analytical Performance . Journal of Analytical Atomic Spectrometry . 2000 . 9 . 15 . 1261–1269.
  23. Web site: Marcia Kaye . Seeing Into The Soul of Cells . University of Toronto . September 13, 2011.
  24. Web site: Lifetime Achievement Award in Plasma Spectrochemistry . Spectroscopyonline . 2020-01-13.
  25. Web site: HUPO Awards - 2019 RECIPIENTS . HUPO . 2019.
  26. News: CyTOF Inventors Receive Prestigious Science and Technology Award from the Human Proteome Organization (HUPO) . Bloomberg . Bloomberg.com . September 18, 2019.
  27. Web site: AIMBE College of Fellows Class of 2014 . AIMBE . 2014.
  28. Web site: U of T's 2011 Inventor of the Year . UToronto . 2011.
  29. Nicolò Omenetto . Greet de Loos . Elsevier/Spectrochimica Acta Atomic Spectroscopy Award 2002 . Spectrochimica Acta Part B: Atomic Spectroscopy . 20 September 2004 . 59 . 9 . 1335 . 10.1016/j.sab.2004.08.002 . 2004AcSpe..59.1335O . en . 0584-8547.
  30. Web site: Manning Awards - Award of Distinction . Manningawards . 2001. https://web.archive.org/web/20160817084835/http://www.manningawards.ca/en/awards/winners/2001/dr-scott-tanner-dr-vladimir-barnov . 2016-08-17 .
  31. News: Gwyn Morgan . Manning Award laureates on the cutting edge . TheGlobeAndMail.com . The Globe and Mail . Feb 8, 2010. https://web.archive.org/web/20140214063634/http://www.theglobeandmail.com:80/report-on-business/rob-commentary/manning-award-laureates-on-the-cutting-edge/article4325666/ . 2014-02-14 .
  32. Web site: 1999 Pittcon Editors' Awards . OOcities.org . May 1999.
  33. Web site: Fellow of the Royal Society of Chemistry . RSC.org.
  34. Web site: Fellow of the American Institute for Medical and Biological Engineering . AIMBE.org . 2014.
  35. Sean C. Bendall . Erin F. Simonds . Peng Qiu . El-ad D. Amir . Peter O. Krutzik . Rachel Finck . Robert V. Bruggner . Rachel Melamed . Angelica Trejo . Olga I. Ornatsky . Robert S. Balderas . Sylvia K. Plevritis . Karen Sachs . Dana Pe’er . Scott D. Tanner . Garry P. Nolan . Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum . Science . May 2011 . 332 . 6030 . 6813–6822 . American Association for the Advancement of Science. 10.1126/science.1198704 . 21551058 . 3273988 . 2011Sci...332..687B .
  36. Olga Ornatsky . Dmitry Bandura . Vladimir Baranov . Mark Nitz . Mitchell A Winnik . Scott Tanner . Highly Multiparametric Analysis by Mass Cytometry . Journal of Immunological Methods . September 2010 . 361 . 1–2 . 1–20 . Elsevier. 10.1016/j.jim.2010.07.002 . 20655312 .
  37. Dmitry R Bandura . Vladimir I Baranov . Olga I Ornatsky . Alexei Antonov . Robert Kinach . Xudong Lou . Serguei Pavlov . Sergey Vorobiev . John E Dick . Scott D Tanner . Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry . Analytical Chemistry . Aug 2009 . 81 . 16 . 6813–6822 . American Chemical Society. 10.1021/ac901049w . 19601617 .
  38. Scott D. Tanner . Vladimir I. Baranov . Dmitry R. Bandura . Reaction Cells and Collision Cells for ICP-MS: A Tutorial Review . Spectrochimica Acta Part B: Atomic Spectroscopy . September 2002 . 57 . 9 . 1361–1452 . Elsevier. 10.1016/S0584-8547(02)00069-1 . 2002AcSpe..57.1361T .
  39. Vladimir I. Baranov . Zoë Quinn . Dmitry R. Bandura . Scott D. Tanner . A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection . Analytical Chemistry . April 2002 . 74 . 7 . 1629–1636 . American Chemical Society. 10.1021/ac0110350 . 12033255 .
  40. Dmitry R. Bandura . Vladimir I. Baranov . Scott D. Tanner . Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell . Analytical Chemistry . April 2002 . 74 . 7 . 1497–1502 . American Chemical Society. 10.1021/ac011031v . 12033236 .
  41. Dmitry R. Bandura . Vladimir I. Baranov . Scott D. Tanner . Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS . Fresenius' Journal of Analytical Chemistry . July 2001 . 370 . 5 . 454–470 . Springer-Verlag. 10.1007/s002160100869 . 11496972 . 20007527 .
  42. Scott D. Tanner . Vladimir I. Baranov . Uwe Vollkopf . A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III. . Journal of Analytical Atomic Spectrometry . August 2000 . 15 . 9 . 1261–1269 . Royal Society of Chemistry. 10.1039/b002604m .
  43. Scott D. Tanner . Vladimir I. Baranov . November 1999 . A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Produced within the Cell . Journal of the American Society for Mass Spectrometry . Springer-Verlag . 10 . 11 . 1083–1094 . 10.1016/S1044-0305(99)00081-1 . 93608392.
  44. Scott D. Tanner . Vladimir I. Baranov . Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS . Atomic Spectroscopy - Norwalk Connecticut . March 1999 . 20 . 45–52 . Atomic Spectroscopy.
  45. Scott D. Tanner . Characterization of Ionization and Matrix Suppression in Inductively Coupled 'Cold' Plasma Mass Spectrometry . Journal of Analytical Atomic Spectrometry . January 1995 . 10 . 11 . The Royal Society of Chemistry . The Royal Society of Chemistry.
  46. Scott D Tanner . Space Charge in ICP-MS: Calculation and Implications . Spectrochimica Acta Part B: Atomic Spectroscopy . June 1992 . 47 . 6 . 809–823 . Elsevier. 10.1016/0584-8547(92)80076-S . 1992AcSpe..47..809T .
  47. George R. Gillson . Donald J. Douglas . John E. Fulford . Kenneth W Halligan . Scott D. Tanner . Nonspectroscopic Interelement Interferences in Inductively Coupled Plasma Mass Spectrometry . Analytical Chemistry . July 1988 . 60 . 14 . 1472–1474 . American Chemical Society. 10.1021/ac00165a024 .

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