Saturnino Calderón de la Barca y Collantes (1799–1864) was a Spanish noble and politician who served as Minister of State from 1858 to 1863, during the reign of Queen Isabella II of Spain and in a cabinet headed by Leopoldo O'Donnell, 1st Duke of Tetuan.
He was born at Reinosa, the eldest son of Manuel Santiago Calderón de la Barca y Rodríguez-Fontecha, Senator for Cantabria, and his wife Saturnina Collantes y Fonegra. His younger brother Fernando Calderón de la Barca, 1st Marquis of Reinosa was also a prominent politician who held important offices.
Among other honours, Calderón was appointed Knight Grand Cross of the Orders of Charles III, Isabella the Catholic, Pius IX, the Légion d'honneur, the Immaculate Conception of Vila Viçosa, the Ludwigsorden, the Dannebrog, the Polar Star, the Royal Guelphic Order and Saint Januarius, and Knight Grand Cordon of the Order of Leopold of Belgium.
He died at Madrid in 1864.
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