| Sargis Manasyan | |
| Office1: | Minister of Interior of the First Republic of Armenia (Acting) |
| Primeminister1: | Hovhannes KatchaznouniAlexander Khatisyan |
| Term Start1: | April 27, 1919 |
| Term End1: | August 10, 1919 |
| Predecessor1: | Alexander Khatisian |
| Successor1: | Abraham Gyulkhandanyan |
| Nationality: | Armenian |
Sargis Manasyan (Armenian: Սարգիս Մանասյան) was an Armenian politician who served as acting Minister of Interior of First Republic of Armenia in 1919. He was also member of Armenian Revolutionary Federation party.[1]