| Sergei Lukashin | |
| Birth Name: | Sargis Srapionyan |
| Office1: | Chairman of the Council of People's Commissars of Armenia |
| Term Start1: | 1922 |
| Term End1: | 1925 |
| Predecessor1: | Alexander Miasnikian |
| Successor1: | Sargis Hambardzumyan |
| Office2: | First Secretary of the Communist Party of Armenia |
| Term Start2: | 1921 |
| Term End2: | 1922 |
| Predecessor2: | Gevork Alikhanyan |
| Successor2: | Ashot Hovhannisyan |
| Birth Place: | New Nakhichevan, near Rostov-on-Don, Russian Empire |
| Death Place: | Unknown |
| Nationality: | Armenian |
| Alma Mater: | Petersburg University |
| Party: | RSDLP (Bolsheviks) (1906–1918) Russian Communist Party (1918–1937) |
| Otherparty: | Communist Party of Armenia |
| Occupation: | Bolshevik politician |
| Awards: | Order of the Red Banner of Labour |
| Native Name: | |
Sergei Lukyani Lukashin (Armenian: Սարգիս Լուկյանի Լուկաշին; Russian: Сергей Лукьянович Лукашин, born Sargis Srapionyan (Սրապիոնյան); 1883 or 1885 – 1937) was an Armenian Bolshevik politician and Soviet statesman.
Lukashin was born in 1883 or 1885[1] in the Armenian-populated city of New Nakhichevan near Rostov-on-Don in Russia. He studied law at the Petersburg University and graduated in 1910. At first a supporter of the Armenian Social-Democratic Labour Organization, he joined the Bolshevik Party in 1906.[2]
He participated in the Bolsheviks' armed rebellion during the October Revolution, after which he fought on the Southern Front of the Russian Civil War in the Don region. In 1918 he worked in the Cheka and as the secretary of the Moscow regional bureau of the Bolshevik Party. In 1919 he returned to the Don region and occupied various positions there until 1921.
From 1921 to 1922 he was the First Secretary of the Communist Party of Armenia. Between 1922 and 1925 was the Chairman of the Council of People's Commissars of the Armenian SSR (equivalent of a Prime Minister). He oversaw the normalization of conditions and the first steps of industrialization in the Armenian SSR, which was suffering from a severe refugee crisis, famine, and disease in the early 1920s. From 1925 to 1928 he was Vice Chairman of the Council of People's Commissars of the Transcaucasian SFSR and occupied various ministerial positions.
From 1928 to 1937 he occupied various positions at the union level having to do with construction and heavy industry. He was arrested and executed in 1937 during the Great Purge.[3] A number of settlements, streets, and schools in Armenia are named after him.