| Sapucaí River | |
| Pushpin Map: | Brazil |
| Source1 Location: | São Paulo state |
| Source1 Coordinates: | -21.0277°N -47.1889°W |
| Mouth Location: | Rio Grande |
| Mouth Coordinates: | -20.13°N -48.449°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Sapucaí River is a river of São Paulo state in southeastern Brazil. It is a tributary of the Rio Grande.
The river forms to the north of Santo Antônio da Alegria, just north of the BR-265 highway near the border with Minas Gerais, where the Ribeirão do Pinheirinho meets the Ribeirão Tomba-perna. It then flows in a generally northwest direction. The river is dammed twice near São Joaquim da Barra. It continues northwest and enters the Rio Grande upstream from Colômbia, São Paulo.