| Santos Michelena | |
| President: | José Antonio Páez |
| Term Start: | 1841 |
| Term End: | 1845 |
| Predecessor: | Carlos Soublette |
| Successor: | Diego Bautista Urbaneja |
| President2: | José María Carreño |
| Order3: | Minister of Foreign Affairs of Venezuela |
| Term Start3: | 28 May 1830 |
| Term End3: | 8 June 1833 |
| President3: | José Antonio Páez |
| Term Start4: | 29 March 1835 |
| Term End4: | 26 November 1835 |
| President4: | José María Vargas |
| Term Start5: | 12 April 1837 |
| Term End5: | 30 May 1837 |
| Birth Date: | 1797 |
| Birth Place: | Maracay, Aragua |
| Death Date: | 1848 |
| Party: | Conservative Party |
Santos Michelena (1797–1848) was a Venezuelan politician. Born in Maracay, Aragua. He was the vice president of Venezuela from 1841 until 1845. He also served as Minister of Foreign Affairs of Venezuela three times, under three different presidents. He was the Minister of Finance from 1830 to 1833, from 1834 to 1835 and in 1837.[1]