| Santo Tomás District | |
| Native Name: | Distrito de Santo Tomás |
| Native Name Lang: | es |
| Settlement Type: | District |
| Mapsize: | frameless |
| Subdivision Type: | Country |
| Subdivision Name: |  Peru |
| Subdivision Type1: | Region |
| Subdivision Name1: | Amazonas |
| Subdivision Type2: | Province |
| Subdivision Name2: | Luya |
| Parts Type: | Subdivisions |
| Parts Style: | para |
| Established Title: | Founded |
| Seat Type: | Capital |
| Seat: | Santo Tomás |
| Leader Title: | Mayor |
| Leader Name: | Enrique Rituay Chávez (2019 - 2022) |
| Unit Pref: | Metric |
| Area Total Km2: | 84.93 |
| Elevation M: | 2525 |
| Population Total: | 3012 |
| Population As Of: | 2017 |
| Population Density Km2: | auto |
| Timezone1: | PET |
| Utc Offset1: | -5 |
| Blank Name Sec1: | UBIGEO |
| Blank Info Sec1: | 010521 |
Santo Tomás is one of 23 districts of the province of Luya in the Amazonas region of Peru. Santo Tomás is located in the mountains and can have a severe climate. The Saint Tomás region has beautiful cataracts and several ruins of the Chachapoya culture.
The district was created at the time of independence and has an estimated population greater than 4,000 inhabitants. Its capital is the town of Santo Tomás. The annual feast of the patron saint is held in the capital on December 21. Santo Tomás is home to the parish of Santo Tomás District and is served by the Sisters of Charity of Sacred Heart of Jesus and the Priests of the Magdalena District, Chachapoyas Province.
In the north the district borders with the San Juan de Lopecancha District, in the East with the La Jalca District (Chachapoyas Province) and the Leimebamba District (Chachapoyas Province), in the south with the San Francisco del Yeso District, in the south-west with the Cocabamba District and in the west with María District.