| Building Name: | Church of San Stefano |
| Location: | Venice, Italy |
| Coordinates: | 45.4332°N 12.3302°W |
| Map Type: | Venezia#Italy |
| Religious Affiliation: | Roman Catholic |
| Province: | Venice |
| Architecture: | yes |
| Architecture Type: | Church |
| Architecture Style: | Gothic |
| Year Completed: | 15th century |
The Chiesa di Santo Stefano (Church of St. Stephen) is a large Roman Catholic church at the northern end of the Campo Santo Stefano in the sestiere of San Marco, Venice, Italy.
It was founded in the 13th century, rebuilt in the 14th century and altered again early in the 15th century, when the fine gothic doorway and ship's keel roof were added. The tall interior is also Gothic in style and has three apses.
Santo Stefano is parish church of one of the parishes in the Vicariate of San Marco-Castello. The other churches of the parish are San Samuele, San Maurizio, San Vidal and the Oratorio di San Angelo degli Zoppi.