| Santo Domingo del Estado | |
| Native Name: | Xuman' Lii |
| Native Name Lang: | trs |
| Settlement Type: | Municipal agency & town |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Map Alt: | 260 |
| Pushpin Map Caption: | Location in Mexico |
| Coordinates: | 17.1558°N -97.8472°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Putla Villa de Guerrero |
| Unit Pref: | Metric |
| Elevation M: | 2718 |
| Population Total: | 927 |
| Population As Of: | 2010 |
| Population Density Km2: | auto |
| Timezone1: | Central Standard Time |
| Utc Offset1: | 6 |
| Timezone1 Dst: | Central Daylight Time |
| Utc Offset1 Dst: | 5 |
| Postal Code Type: | Postal code |
| Postal Code: | 71010 |
Santo Domingo del Estado is a town and municipal agency inhabited by trique Indians in the municipality of Putla Villa de Guerrero, Oaxaca, Mexico. In this town speak the trique language. Trique language name is Xuman' Lii which means "small town".
Santo Domingo del Estado has basic level school, e.g.:
Children go to secondary school and high school in Chicahuaxtla.
In this town there is a clinic provided by the Secretariat of Health (SSA) of the Mexican government, this clinic is run by a doctor and a person elected by the people. These people have the "Popular Insurance" provided by the Mexican government too.
These natives like to play basketball and football. The festivities are held tournaments.