| Santo Domingo Tomaltepec | |
| Settlement Type: | Municipality and town |
| Pushpin Map: | Mexico |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Area Total Km2: | 49.76 |
| Population As Of: | 2005 |
| Population Total: | 2,303 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Coordinates: | 17.0667°N -133°W |
| Elevation M: | 1590 |
Santo Domingo Tomaltepec is a town and municipality in Oaxaca in south-western Mexico. It is part of the Centro District in the Valles Centrales region, about 10 km east of the city of Oaxaca. The municipality covers an area of 49.76 km2. The climate is mild, with little change throughout the year.Natural vegetation is semi-desert, but agricultural production of maize, beans and fruit in the heavy clay soils is highly productive.[1]
As of 2005, the municipality had 585 households with a total population of 2,303, of whom 347 spoke an indigenous language.[1]