| Santo Domingo | |
| Settlement Type: | Municipality and town |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | San Luis Potosí |
| Leader Title: | Presidente Municipal |
| Leader Name: | Fili Rodriguez |
| Population As Of: | 2005 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Coordinates: | 22.865°N -100.285°W |
Santo Domingo is a town and municipality in the Mexican state of San Luis Potosí in central Mexico.[1]