| Official Name: | Santo Antônio do Itambé |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location in Brazil |
| Coordinates: | -18.4658°N -43.3069°W |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | Southeast |
| Subdivision Type2: | State |
| Subdivision Name2: | Minas Gerais |
| Subdivision Type3: | Mesoregion |
| Subdivision Name3: | Metropolitana de Belo Horizonte |
| Subdivision Type4: | Microregion |
| Subdivision Type5: | Metrop. region |
| Established Date: | December 30, 1962 [1] |
| Leader Party: | PDT |
| Leader Title: | Mayor |
| Leader Name: | Ronam Sales [2] |
| Area Total Km2: | 305.74 |
| Population Total: | 3,799 |
| Population As Of: | 2020 [3] |
| Population Density Km2: | auto |
| Blank Name Sec1: | HDI |
| Timezone1: | BRT |
| Utc Offset1: | -3 |
| Postal Code Type: | Postal code |
| Postal Code: | 39160-000 |
| Area Code Type: | Area code |
| Area Code: | 33 |
Santo Antônio do Itambé is a municipality in the state of Minas Gerais, Brazil. The population is 3,799 (2020 est.) in an area of 305.74 km².[4]
The municipality contains part of the Pico do Itambé State Park, created in 1998.