| Official Name: | Santo Antônio do Içá |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location in Brazil |
| Coordinates: | -3.1019°N -67.94°W |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | North |
| Subdivision Type2: | State |
| Subdivision Name2: | Amazonas |
| Subdivision Type3: | Mesoregion |
| Subdivision Type4: | Microregion |
| Subdivision Name4: | Alto Solimões |
| Subdivision Type5: | Metrop. region |
| Leader Title: | Mayor |
| Area Total Km2: | 12307 |
| Population Total: | 21,243 |
| Population As Of: | 2020 |
| Population Density Km2: | auto |
| Timezone1: | AMT |
| Utc Offset1: | -4 |
| Postal Code Type: | Postal code |
| Postal Code: | 69680-xxx |
| Area Code Type: | Area code |
| Area Code: | +55 97 |
Santo Antônio do Içá is a community and a municipality in the state of Amazonas near the Colombian border in Brazil. The population is 21,243 (2020 est.)[1] in an area of 12,307 km².[2] The municipality was created in 1955 out of São Paulo de Olivença. The city is served by Ipiranga Airport.
The municipality contains the Javari-Buriti Area of Relevant Ecological Interest, created in 1985.It contains parts of the Jutaí-Solimões Ecological Station.