| Official Name: | Santo Antônio do Amparo |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location in Brazil |
| Coordinates: | -20.9458°N -44.9189°W |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | Southeast |
| Subdivision Type2: | State |
| Subdivision Name2: | Minas Gerais |
| Subdivision Type3: | Mesoregion |
| Subdivision Type4: | Microregion |
| Subdivision Type5: | Metrop. region |
| Leader Title: | Mayor |
| Area Total Km2: | 488.89 |
| Population Total: | 18,613 |
| Population As Of: | 2020 [1] |
| Population Density Km2: | auto |
| Timezone1: | BRT |
| Utc Offset1: | -3 |
| Postal Code Type: | Postal code |
| Postal Code: | 37262-xxx |
| Area Code Type: | Area code |
| Area Code: | +55-37 |
Santo Antônio do Amparo is a city in the southern part of the state of Minas Gerais, Brazil. The population is 18,613 (2020 est.) in an area of 488.89 km2.[2] The municipality was founded in 1938.