| Official Name: | Santo Amaro |
| Mapsize: | 250px |
| Image Map1: | Estação Santo Amaro.jpg |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | State |
| Subdivision Name1: | São Paulo |
| Subdivision Type2: | City |
| Subdivision Name2: | São Paulo |
| Government Type: | Subprefecture |
| Leader Title: | Subprefect |
| Leader Name: | Ailton Araujo Brandão |
| Area Total Km2: | 15.6 |
| Population As Of: | 2000 |
| Population Total: | 52.411 |
| Population Density Km2: | 3.360 |
| Blank Name: | HDI |
| Blank Info: | 0.943 –high |
| Website: | Subprefecture of Santo Amaro |
Santo Amaro is a district in the subprefecture of the same name in the southern area of the city of São Paulo, Brazil. It was formerly a separate municipality until 1933, when it was incorporated to the municipality of São Paulo.
A German school, Ginasio Humboldt Santo Amaro, was previously in Santo Amaro.[1]