| Santiago Yosondúa | |
| Settlement Type: | Municipality and town |
| Pushpin Label Position: | above |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Area Total Km2: | 215.61 |
| Population As Of: | 2005 |
| Population Total: | 7,197 |
| Population Urban: | 1,674 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Postal Code Type: | Postal code |
| Postal Code: | 71180 |
Santiago Yosondúa is a town and municipality in Oaxaca in south-western Mexico. The municipality covers an area of 215.61 km². It is part of the Tlaxiaco District in the south of the Mixteca Region.
As of 2005, the municipality had a total population of 7,197.[1]