| Santiago Villafañe | |
| Fullname: | Santiago Hernán Villafañe |
| Height: | 1.79 m |
| Birth Date: | 19 May 1988 |
| Birth Place: | Mar del Plata, Argentina |
| Position: | Right-back, centre-back |
| Youthyears1: | –2001 |
| Youthyears2: | 2001–2007 |
| Youthclubs1: | Club Deportivo Norte[1] |
| Youthclubs2: | Boca Juniors |
| Years1: | 2006–2011 |
| Years2: | 2007–2009 |
| Years3: | 2011–2012 |
| Years4: | 2012–2014 |
| Years5: | 2014 |
| Years6: | 2015 |
| Years7: | 2015 |
| Years8: | 2016 |
| Years9: | 2016 |
| Years10: | 2017 |
| Years11: | 2017–2018 |
| Years12: | 2019 |
| Years13: | 2020–2021 |
| Clubs1: | Boca Juniors |
| Clubs2: | → Real Madrid Castilla (loan) |
| Clubs3: | Independiente Rivadavia |
| Clubs4: | Midtjylland |
| Clubs5: | Alimos |
| Clubs6: | Panthrakikos |
| Clubs7: | OFI Crete |
| Clubs8: | Colón |
| Clubs9: | RNK Split |
| Clubs10: | Montana |
| Clubs11: | Ruch Chorzów |
| Clubs12: | Thesprotos |
| Clubs13: | JJ Urquiza |
| Caps1: | 7 |
| Caps2: | 22 |
| Caps3: | 11 |
| Caps4: | 11 |
| Caps5: | 11 |
| Caps6: | 4 |
| Caps8: | 7 |
| Caps9: | 1 |
| Caps10: | 7 |
| Caps11: | 18 |
| Caps12: | 11 |
| Caps13: | 20 |
| Goals1: | 0 |
| Goals2: | 0 |
| Goals3: | 0 |
| Goals4: | 0 |
| Goals5: | 0 |
| Goals6: | 0 |
| Goals8: | 0 |
| Goals9: | 0 |
| Goals10: | 0 |
| Goals11: | 0 |
| Goals12: | 0 |
| Goals13: | 0 |
Santiago Hernán Villafañe (born 19 May 1988) is an Argentine former professional footballer who played as a defender.
Santiago Hernán Villafañe began his playing career in Argentina with Boca Juniors, with whom he debuted in the First Division. A predominantly left sided player, he is known for his tough tackling and speed.
In 2007, he joined Real Madrid from Boca Juniors, where he played as a wingback or midfielder for Real Madrid Castilla. Villafañe trained with the first team on several occasions but did not play for Real Madrid in La Liga.
In 2009 Villafañe returned to Boca Juniors.
In July 2012 he signed a five-year contract with the Danish Superliga-side FC Midtjylland.[2]
In summer 2016, he signed for the Croatian club of RNK Split, in order to help the team to achieve the team's wish to win the Croatian First Football League.
On 23 February 2017, Villafañe signed with Bulgarian club Montana until the rest of the season.[3]
On 18 July 2017, Villafañe signed a 1-year contract with Polish I liga side Ruch Chorzów with an option for a further year.[4]