| Santiago Papasquiaro | |
| Settlement Type: | Municipal Seat and city |
| Pushpin Map: | Mexico Durango#Mexico |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Durango |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Santiago Papasquiaro |
| Established Date: | 22 July 1597 |
| Area Total Km2: | 7,238 |
| Area Total Sq Mi: | 2,794 |
| Population As Of: | 2015 |
| Population Total: | 26,121 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | Central |
| Utc Offset: | -6 |
| Coordinates: | 25.0439°N -105.4192°W |
| Elevation M: | 1,750 |
| Elevation Ft: | 5,742 |
| Postal Code: | 34630 |
| Area Code: | 674 |
Santiago Papasquiaro is a city located in a valley situated on the eastern slopes of the Sierra Madre Occidental in the Mexican state of Durango. As of 2010, the city of Santiago Papasquiaro had a population of 26,121,[1] while the municipality has a census population of 48,482 as of 2015.[2] It is the fourth largest community in the state in terms of population, and is the municipal seat of the municipality of the same name. The municipality has an area of 7238.4km2.
During the past few years, the city's infrastructure has improved vastly. Agriculture is a vital part of the city's economy. Santiago Papasquiaro is also the home of Mexican Army's 71st Infantry Battalion barracks.