| Official Name: | Santiago, Missouri |
| Pushpin Map: | Missouri#USA |
| Pushpin Label: | Santiago |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Benton |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 843 |
| Coordinates: | 38.4269°N -93.4569°W |
| Area Code: | 660 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 741241 |
Santiago is an unincorporated community in Benton County, Missouri, United States. Santiago is located along Supplemental Route E, 7.1miles west-northwest of Lincoln.[1]
A post office called Santiago was established in 1899, and remained in operation until 1904.[2] The community's name commemorates the Siege of Santiago.[3]