| Santa Sofia d'Epiro | |
| Official Name: | Comune di Santa Sofia d'Epiro |
| Native Name: | aae|Shën Sofia e Epirit |
| Coordinates: | 39.55°N 36°W |
| Region: | Calabria |
| Province: | Cosenza (CS) |
| Mayor: | Daniele Atanasio Sisca |
| Area Total Km2: | 39.22 |
| Population Total: | 2500 |
| Population As Of: | 31 August 2018 |
| Population Demonym: | Sofioti (Albanese: Shënsofjotë) |
| Elevation M: | 558 |
| Postal Code: | 87048 |
| Area Code: | 0984 |
Santa Sofia d'Epiro (aae|Shën Sofia e Epirit) is an Arbëresh town and comune in the province of Cosenza in the Calabria region of southern Italy.
The town is bordered by Acri, Bisignano, San Demetrio Corone and Tarsia.