| Santa Rosa del Sur | |
| Settlement Type: | Municipality and town |
| Mapsize: | 250px |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Colombia |
| Subdivision Type: | Country |
| Subdivision Name: |  Colombia |
| Subdivision Type1: | Department |
| Subdivision Name1: | Bolívar Department |
| Area Total Km2: | 2800 |
| Population As Of: | 2015 |
| Population Total: | 42003 |
| Population Urban: | 22563 |
| Timezone: | Colombia Standard Time |
| Utc Offset: | -5 |
| Elevation M: | 650 |
San Rosa del Sur (pronounced as /es/) is a town and municipality located in the Bolívar Department, northern Colombia, around 720 km away from the department's capital, Cartagena.