| Santa Rosa | |
| Native Name Lang: | es |
| Settlement Type: | City |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Santa Rosa in Argentina |
| Coordinates: | -33.25°N -77°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Mendoza |
| Subdivision Type2: | Department |
| Subdivision Name2: | Santa Rosa |
| Unit Pref: | Metric |
| Population Total: | 15818 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | M5596 |
| Area Code Type: | Dialing code |
| Area Code: | +54 2623 |
| Blank Name: | Climate |
| Blank Info: | BWk |
Santa Rosa is a city in the center-north of the province of Mendoza, Argentina, located on the northern shore of the Tunuyán River, by National Route 7, south-east from the provincial capital Mendoza. It has 15,818 inhabitants as per the, and is the head town of the Santa Rosa Department.