| Santa Marina Salina | |
| Official Name: | Comune di Santa Marina Salina |
| Coordinates: | 38.5667°N 66°W |
| Region: | Sicily |
| Metropolitan City: | Messina (ME) |
| Frazioni: | Lingua |
| Mayor: | Domenico Arabia |
| Area Total Km2: | 8.78 |
| Population Footnotes: | [1] |
| Population Total: | 858 |
| Population As Of: | 31 December 2023 |
| Population Demonym: | Santamarienesi |
| Elevation M: | 25 |
| Postal Code: | 98050 |
| Area Code: | 090 |
Santa Marina Salina is a comune (municipality) and one of the main towns on Salina, one of the Aeolian Islands. It is situated in the Metropolitan City of Messina in the Italian region Sicily, located about 140km (90miles) northeast of Palermo and about 70km (40miles) northwest of Messina.
Santa Marina Salina borders the municipalities of Leni and Malfa.