| Santa Lucia di Serino | |
| Official Name: | Comune di Santa Lucia di Serino |
| Coordinates: | 40.8667°N 66°W |
| Province: | (AV) |
| Mayor: | Fenisia Mariconda |
| Area Total Km2: | 3 |
| Population Footnotes: | [1] |
| Population Total: | 1460 |
| Population As Of: | 31 December 2010 |
| Elevation M: | 400 |
| Saint: | Saint Lucy |
| Day: | 13 December |
| Postal Code: | 83020 |
| Area Code: | 0825 |
| Istat: | 064088 |
| Frazioni: | San Michele di Serino, Santo Stefano del Sole, Serino |
Santa Lucia di Serino is a town and comune in the province of Avellino, Campania, southern Italy.