| Official Name: | Santa Lucía Cotzumalguapa |
| Settlement Type: | Municipality and town |
| Pushpin Map: | Guatemala |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Guatemala |
| Coordinates: | 14.35°N -91.0167°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Guatemala |
| Subdivision Type1: | Department |
| Subdivision Name1: | Escuintla Department |
| Leader Title: | Mayor |
| Leader Title1: | for places with, say, both a mayor and a city manager |
| Unit Pref: | Imperial |
| Area Total Km2: | 530 |
| Elevation M: | 372 |
| Population Footnotes: | [1] |
| Population Total: | 112780 |
| Population As Of: | 2018 census |
| Population Density Km2: | auto |
| Blank Name: | Climate |
| Blank Info: | Am |
Santa Lucía Cotzumalguapa (pronounced as /es/) is a town, with a population of 58,877 (2018 census),[2] and a municipality in the Escuintla department of Guatemala.
The municipality includes the Cotzumalhuapa archaeological zone, including the pre-Columbian archaeological sites of El Baúl and Bilbao. It is the birthplace of president Carlos Castillo Armas.
Santa Lucía Cotzumalguapa has a tropical monsoon climate (Köppen: Am).
The town has a team that plays in the Liga Nacional de Guatemala, the top division soccer league in Guatemala.