| Santa Isabel, Tolima | |
| Settlement Type: | Municipality and town |
| Mapsize: | 250px |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Colombia |
| Subdivision Type: | Country |
| Subdivision Type1: | Department |
| Subdivision Name1: | Tolima Department |
| Area Total Km2: | 416 |
| Population As Of: | 2016 |
| Population Total: | 6382 |
| Timezone: | Colombia Standard Time |
| Utc Offset: | -5 |
| Elevation M: | 2250 |
Santa Isabel (pronounced as /es/) is a town and municipality in the Tolima department of Colombia. The population of the municipality was 6,220 as of the 1993 census.