| Santa Isabel | |
| Settlement Type: | Town |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Chihuahua |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Santa Isabel |
| Population As Of: | 2010 |
| Population Total: | 1,378 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Coordinates: | 28.3422°N -106.3683°W |
Santa Isabel is a small town in the Mexican state of Chihuahua. It serves as the municipal seat for the surrounding municipality of Santa Isabel.
As of 2010, the town of Santa Isabel had a population of 1,378,[1] down from 1,412 as of 2005.[2]