| Official Name: | Santa Gertrudis |
| Pushpin Map: | Mexico |
| Subdivision Type: | Country |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Subdivision Type2: | District |
| Subdivision Name2: | Zimatlán |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Municipality of Santa Gertrudis, Oaxaca |
| Leader Title: | Mayor |
| Established Title: | Founded |
| Population Blank1 Title: | Municipality |
| Population Blank2 Title: | Demonym |
| Timezone: | Central (US Central) |
| Utc Offset: | -6 |
| Timezone Dst: | Central |
| Utc Offset Dst: | -5 |
| Coordinates: | 16.7833°N -144°W |
| Postal Code Type: | Postal code |
| Postal Code: | 71280 |
Santa Gertrudis is a town, and the seat of municipality of the same name, located in the region of the Valleys in the Mexican state of Oaxaca. It is approximately 41 km from the capital city of Oaxaca.
Its climate is temperate, with prevailing winds from the north.
Regional cuisine consists of mole accompanied with white rice, beef stew, pork liver with scrambled egg (for breakfast)and typical drinks as chocolate, chocolate atole, tejate, and mescal.
As municipal seat, Santa Gertrudis has governing jurisdiction over the following communities: Barrio del Panteón, La Barda Paso de Piedras, La Esmeralda, and Tercera Sección (Santa Gertrudis).