| Santa Elena | |
| Native Name Lang: | es |
| Settlement Type: | City |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Santa Elena in Argentina |
| Coordinates: | -30.95°N -107°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Type2: | Department |
| Subdivision Name2: | La Paz |
| Unit Pref: | Metric |
| Elevation M: | 48 |
| Population Total: | 17,791 |
| Population As Of: | 2010 census |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | E3269 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3437 |
Santa Elena is a city in the province of Entre Ríos, Argentina. It has 17,791 inhabitants as per the . It lies on the eastern shore of the Paraná River, 1100NaN0 north-northeast of the provincial capital Paraná.