| Santa Domenica Talao | |
| Official Name: | Comune di Santa Domenica Talao |
| Coordinates: | 39.8167°N 66°W |
| Province: | (CS) |
| Mayor: | Alfredo Giuseppe Lucchesi |
| Area Total Km2: | 35 |
| Population Total: | 1300 |
| Population As Of: | 2007 |
| Population Demonym: | Santadomenicani |
| Elevation M: | 304 |
| Saint: | San Giuseppe |
| Postal Code: | 87020 |
| Area Code: | 0985 |
Santa Domenica Talao is a village and comune in the province of Cosenza in the Calabria region of southern Italy. It is located 304 [1] meters above sea-level and overlooks the Lao river valley. The local church is dedicated to San Giuseppe and hold a festival here every July 20.