| Official Name: | Santa Cruz Canton |
| Settlement Type: | Canton |
| Flag Size: | 100px |
| Seal Size: | 80px |
| Subdivision Type: | Country |
| Subdivision Name: |  Ecuador |
| Subdivision Type1: | Province |
| Subdivision Name1: | Galápagos Province |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Puerto Ayora |
| Area Total Km2: | 1804 |
| Population As Of: | 2022 census |
| Population Footnotes: | [1] |
| Population Total: | 17233 |
| Population Density Km2: | auto |
| Coordinates: | -0.6333°N -112°W |
| Elevation M: | 633 |
Santa Cruz is a canton in the Ecuadorian province of the Galápagos. Its area covers the islands of Baltra, Bartolomé, Marchena, North Seymour, Pinta, Pinzón, Rábida, Santa Cruz, and Santiago. As of the 2006 Galápagos census, it has a population of 11,262. [2]