| Santa Bárbara | |
| Official Name: | Santa Bárbara del Zulia |
| Pushpin Map: | Venezuela |
| Subdivision Type: | Country |
| Subdivision Type1: | State |
| Subdivision Type2: | Municipality |
| Subdivision Name: | Venezuela |
| Subdivision Name1: | Zulia |
| Subdivision Name2: | Colón Municipality |
| Established Title: | Founded |
| Established Date: | 1704 |
| Population Total: | 80000 (estimate) |
| Timezone: | VET |
| Utc Offset: | -4 |
| Coordinates: | 9°N -71.95°W |
| Elevation M: | 7 |
| Population Blank1 Title: | Demonym |
| Population Blank1: | Barbarense |
| Blank1 Name: | Climate |
Santa Bárbara del Zulia is a city of some 80,000 inhabitants in Zulia State in Venezuela. It is located to the south-west of Maracaibo Lake, in the Sur del Lago region of the state. Governor and presidential candidate Manuel Rosales was born in this city on December 12, 1952.
Santa Bárbara is connected by two bridges across the Escalante River with the city of San Carlos del Zulia, forming a twin city.