| Official Name: | Santa Bárbara (Potosí) |
| Settlement Type: | Town |
| Pushpin Label Position: | bottom |
| Subdivision Type: | Country |
| Subdivision Name1: | Potosí Department |
| Subdivision Type2: | Province |
| Subdivision Name2: | Sud Chichas Province |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Atocha Municipality |
| Unit Pref: | Imperial |
| Population As Of: | 2001 |
| Population Total: | 2505 |
| Timezone: | BST |
| Utc Offset: | -4 |
Santa Bárbara is a small town in the Sud Chichas Province of the Potosí Department in Bolivia.
The town lies at an altitude of 4774 m at the foot of Cerro Chorolque, a 5552 m high mountain, rich in ore deposits of tin, bismuth, silver, gold and copper, and exploited by the mine "Chorolque" from different sides. It also was the highest permanent settlement of the Inca Empire.