| Official Name: | Sta. Ana de Yusguare |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | Choluteca |
| Settlement Type: | Municipality |
| Coordinates: | 13.3°N -94°W |
Santa Ana de Yusguare (pronounced as /es/) is a municipality in the Honduran department of Choluteca.[1]