| Official Name: | Santa Ana |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | La Paz |
| Area Total Km2: | 198 |
| Population As Of: | 2015 |
| Settlement Type: | Municipality |
| Population Total: | 12121 |
| Population Density Km2: | auto |
| Coordinates: | 14.0667°N -144°W |
Santa Ana is a municipality in the Honduran department of La Paz, known for its high crime rate.
At the time of the 2013 Honduras census, Santa Ana municipality had a population of 11,777. Of these, 95.56% were Indigenous (95.46% Lenca), 4.25% Mestizo, 0.13% Black or Afro-Honduran and 0.06% others.[1]