| Official Name: | Santa Ana |
| Settlement Type: | Barangay |
| Blank Emblem Type: | Wordmark |
| Pushpin Map: | Metro Manila |
| Subdivision Type: | Country |
| Subdivision Name: | Philippines |
| Subdivision Type1: | Region |
| Subdivision Name1: | National Capital Region |
| Subdivision Type2: | City |
| Subdivision Name2: | Taguig |
| Subdivision Type3: | District |
| Subdivision Name3: | 1st Legislative district of Taguig |
| Named For: | Saint Anne |
| Government Type: | Barangay |
| Leader Title: | Punong Barangay |
| Leader Name: | Roberto " Obet" M. Flogen |
| Established Date: | April 04, 1587 |
| Area Total Km2: | 0.22 |
| Population As Of: | 2020 |
| Population Total: | 22,581 |
| Population Density Km2: | auto |
| Timezone: | PST |
| Utc Offset: | +8 |
| Coordinates: | 14.5277°N 121.0766°W |
| Postal Code Type: | Postal Code |
| Postal Code: | 1637 |
| Area Code: | 02 |
| Website: | https://www.facebook.com/brgystaanataguig |
Santa Ana is one of the 38 barangays of Taguig, Metro Manila, Philippines. It is one of the nine original barrios of Taguig.[1] It is named after Saint Anne, who is the patroness of the barangay.
Santa Ana is the original municipal center of Taguig from its establishment in 1587, during the Spanish colonization of the Philippines.[2] [3] It had a total land area of .
The Archdiocesan Shrine of St. Anne is a Roman Catholic church located in the barangay. Built in 1587, it is situated next to the Taguig River and across Plaza Quezon, where the statue of Manuel L. Quezon was erected when he was still serving as the nation's President.[4] The Taguig Integrated School is also located in the barangay. Its Gabaldon Building, which has remained standing since it was constructed from 1917 to 1928 and currently serves as the school's museum.
Santa Ana is bounded to the north by Tuktukan, to the east by Calzada Tipas, to the south by Laguna de Bay, and to the west by the Taguig River.