| Official Name: | Santa Ana |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | top |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | Francisco Morazán |
| Area Total Km2: | 66 |
| Population As Of: | 2015 |
| Settlement Type: | Municipality |
| Population Total: | 16439 |
| Population Density Km2: | auto |
| Coordinates: | 13.9333°N -103°W |
Santa Ana is a municipality in the Honduran department of Francisco Morazán.
The location of the crash of Central American Airways Flight 731 was El Espino in Santa Ana.[1]