Sant'Andrea is a Roman Catholic church located on Via Vittorio Emanuele in the town of Anagni, province of Frosinone, region of Lazio, Italy.
A church at the site is documented by 1003. Between 1263 and 1276, the church was rebuilt under Bishop Landone Conti in a Gothic style. Of the Romanesque structure, a few structures remain, among them the crypt, which was once part of the Church of San Vito. In the 16th century, Cardinal Benedetto Lomellino refurbished the church; with another restructuring between 1748 and 1751. The present facade was added in 1761. The interior has a single nave. The main altarpieces depict St Andrew: