| Sant'Antonio Abate | |
| Coordinates: | 40.7333°N 47°W |
| Region: | Campania |
| Metropolitan City: | Naples (NA) |
| Frazioni: | Casa Iovine, Salette, Fusara, Cottimo, Buonconsiglio, Pontone |
| Mayor: | Ilaria Abagnale |
| Area Total Km2: | 7.9 |
| Population Footnotes: | [1] |
| Population Total: | 19746 |
| Population As Of: | 31 August 2016 |
| Population Demonym: | Abatesi |
| Elevation M: | 20 |
| Saint: | St Anthony the Abbot |
| Day: | 17 January |
| Postal Code: | 80057 |
| Area Code: | 081 |
Sant'Antonio Abate is a comune (municipality) in the Metropolitan City of Naples in the Italian region Campania, located about 30 km southeast of Naples.
Sant'Antonio Abate borders the following municipalities: Angri, Gragnano, Lettere, Pompei, Santa Maria la Carità, Scafati.