Sanofi–Translate Bio COVID-19 vaccine explained

Type:vaccine
Target:SARS-CoV-2
Vaccine Type:mrna
Legal Status:Terminated[1]
Routes Of Administration:Intramuscular
Synonyms:MRT5500, VAW00001

The Sanofi–Translate Bio COVID-19 vaccine, also known as MRT5500 or VAW00001, was a COVID-19 vaccine candidate developed by Sanofi Pasteur and Translate Bio.[2] [3] The development was stopped in September 2021.[4] __TOC__

History

In June 2020, Sanofi, after lagging behind its competitors, "accelerated" the development of the vaccine via the smaller biotech firm Translate Bio, with a US$425 million partnership.[5]

Development of the vaccine halted in September 2021, with Sanofi citing the difficulty of running placebo-controlled studies with other mRNA vaccines (such as Pfizer's and Moderna's) already on the market. Despite this, the company reported "promising results" in its initial trials.[4] Sanofi has continued testing its recombinant protein vaccine, developed collaboratively with GlaxoSmithKline, to serve as a booster dose for other COVID-19 vaccines.[4]

Notes and References

  1. News: Abboud L . Sanofi stops development of Covid vaccine based on mRNA technology . Financial Times . 28 September 2021.
  2. News: Sanofi and Translate Bio initiate Phase 1/2 clinical trial of mRNA COVID-19 vaccine candidate . 20 March 2021 . Sanofi . 12 March 2021. https://web.archive.org/web/20211009194359/https://www.sanofi.com/en/media-room/press-releases/2021/2021-03-12-07-00-00-2191846. 9 October 2021.
  3. Web site: Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older (VAW00001) . United States National Library of Medicine . 20 March 2021 .
  4. News: Sanofi drops plans for messenger RNA vaccine against virus. 28 September 2021. live. Associated Press. https://web.archive.org/web/20211014003020/https://apnews.com/article/coronavirus-pandemic-technology-business-public-health-coronavirus-vaccine-aeb851722ad9f876395cf8e5af4aea5a. 14 October 2021. 7 October 2021.
  5. News: Branswell H, Feuerstein A . Sanofi, a straggler in the Covid-19 vaccine race, accelerates its plans. 23 June 2020. live. STAT. https://web.archive.org/web/20211020032520/https://www.statnews.com/2020/06/23/sanofi-a-straggler-in-the-covid-19-vaccine-race-accelerates-its-plans/. 20 October 2021. 7 August 2020.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sanofi–Translate Bio COVID-19 vaccine".

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