| Native Name: | Sirem sancağı Sremski sandžak Srijemski sandžak |
| Conventional Long Name: | Sanjak of Syrmia |
| Common Name: | Syrmia |
| Subdivision: | Sanjak |
| Nation: | the Ottoman Empire |
| P1: | Syrmia County (medieval)Syrmia County |
| Flag P1: | Blason louis II de Hongrie.svg |
| P2: | Valkoensis County |
| Flag P2: | Blason louis II de Hongrie.svg |
| S1: | Sanjak of Smederevo |
| Flag S1: | Flag of the Ottoman Empire (Thicker Crescent).svg |
| S2: | Military Frontier |
| Flag S2: | Flag of the Habsburg Monarchy.svg |
| S3: | Kingdom of Slavonia |
| Flag S3: | Flag of the Kingdom of Slavonia.svg |
| Year Start: | 1541 |
| Year End: | 1718 |
| Image Map Caption: | Sanjak of Syrmia in the 17th century |
| Capital: | Uyluk (Turkish: Uyluk: today Ilok) Dimitrofça (Serbian:Dmitrovica, Sremska Mitrovica) |
| Today: | Serbia Croatia |
Sanjak of Syrmia (Turkish: Sirem sancağı, Serbian: Sremski sandžak/Сремски санџак, Croatian: Srijemski sandžak) was an administrative territorial entity of the Ottoman Empire formed in 1541. It was located in the Syrmia region and was part of the Budin Province. Administrative center of the Sanjak of Syrmia was from 1542 Uyluk (Croatian: Ilok) and in the second half of the 17th century it was Dimitrofça (Serbian: Dmitrovica, today Sremska Mitrovica). Most of the sanjak was ceded to Austria according to Treaty of Karlovitz in 1699. Remainder of the territory of sanjak was transferred to Sanjak of Semendire and was later also ceded to Austria according to Treaty of Passarowitz in 1718.
In 1583-87, Sanjak was divided into several nahijas:
In 1667, Sanjak was divided into several kadiluks:
Sanjak was mostly populated by Orthodox Serbs and Muslims of various ethnic origins. Population of villages was entirely Serb, while population of towns and cities was ethnically and religiously diverse. The largest city in sanjak was Dimitrofça (Dmitrovica), which, according to 1545-48 data was mainly populated by Serbs and according to 1566-69 data mainly by Muslims.