Sanguiin H-6 Explained

Sanguiin H-6 is an ellagitannin.

Natural occurrence

Sanguiin H-6 can be found in Rosaceae such as the great burnet (Sanguisorba officinalis),^[1] in strawberries (Fragaria × ananassa)^[2] and in Rubus species such as red raspberries (Rubus idaeus)^{[3] [4]} or cloudberries (Rubus chamaemorus).^[4]

Chemistry

Sanguiin H-6 is dimer of casuarictin linked by a bond between the gallic acid residue and one of the hexahydroxydiphenic acid units. It has sanguisorbic acid ester groups as linking units between glucopyranose moieties.^[5] Sanguiin H-6 contributes to the in vitro antioxidant activity of raspberries.^[6]

External links

• Sanguiin H-6 on www.phenol-explorer.eu

Notes and References

1. Bastow . K. . Bori . I. . Fukushima . Y. . Kashiwada . Y. . Tanaka . T. . Nonaka . G. . Nishioka . I. . Lee . K. -H. . 10.1055/s-2006-959659 . Inhibition of DNA Topoisomerases by Sanguiin H-6, a Cytotoxic Dimeric Ellagitannin fromSanguisorba officinalis1 . Planta Medica . 59 . 3 . 240–245 . 2007 . 8391144. 260281189 .
2. Seeram . N. P. . Lee . R. . Scheuller . H. S. . Heber . D. . Identification of phenolic compounds in strawberries by liquid chromatography electrospray ionization mass spectroscopy . 10.1016/j.foodchem.2005.02.047 . Food Chemistry . 97 . 1–11 . 2006 . 73532960 .
3. Mullen . W. . Stewart . A. J. . Lean . M. E. . Gardner . P. . Duthie . G. G. . Crozier . A. . Effect of freezing and storage on the phenolics, ellagitannins, flavonoids, and antioxidant capacity of red raspberries . Journal of Agricultural and Food Chemistry . 50 . 18 . 5197–5201 . 2002 . 12188629 . 10.1021/jf020141f.
4. Kähkönen . M. . Kylli . P. . Ollilainen . V. . Salminen . J. P. . Heinonen . M. . Antioxidant Activity of Isolated Ellagitannins from Red Raspberries and Cloudberries . 10.1021/jf203431g . Journal of Agricultural and Food Chemistry . 60 . 5 . 1167–1174 . 2012 . 22229937.
5. Vrhovsek . U. . Guella . G. . Gasperotti . M. . Pojer . E. . Zancato . M. . Mattivi . F. . 10.1021/jf2052256 . Clarifying the Identity of the Main Ellagitannin in the Fruit of the Strawberry, Fragaria vesca and Fragaria ananassa Duch . Journal of Agricultural and Food Chemistry . 60 . 10 . 2507–2516 . 2012 . 22339338.
6. Borges . G. . Degeneve . A. . Mullen . W. . Crozier . A. . Identification of Flavonoid and Phenolic Antioxidants in Black Currants, Blueberries, Raspberries, Red Currants, and Cranberries† . 10.1021/jf902263n . Journal of Agricultural and Food Chemistry . 58 . 7 . 3901–3909 . 2010 . 20000747.