| Sanele Mathenjwa | |
| Birth Date: | 5 October 1995 |
| Birth Place: | KwaMashu, South Africa |
| Position: | Midfielder |
| Youthyears1: | –2017 |
| Youthclubs1: | Lamontville Golden Arrows |
| Years1: | 2017–2021 |
| Clubs1: | Lamontville Golden Arrows |
| Caps1: | 7 |
| Goals1: | 0 |
| Years2: | 2021–2022 |
| Clubs2: | Black Leopards |
| Caps2: | 15 |
| Goals2: | 1 |
| Club-Update: | 13 November 2022 |
Sanele Mathenjwa (born 5 October 1995) is a South African soccer player who last played as a midfielder for South African side Black Leopards.[1] He was born in KwaMashu.[2]