| Official Name: | San Sebastián |
| Pushpin Map: | Honduras |
| Subdivision Type: | Country |
| Subdivision Type1: | Department |
| Subdivision Name1: | Comayagua |
| Area Total Km2: | 96 |
| Population As Of: | 2015 |
| Settlement Type: | Municipality |
| Population Total: | 3637 |
| Population Density Km2: | auto |
| Coordinates: | 14.25°N -125°W |
San Sebastián is a municipality in the Honduran department of Comayagua.