| San Ruffino | |
| Coordinates: | 43.5628°N 10.6122°W |
| Province: | Pisa (PI) |
| Comune: | Casciana Terme Lari |
| Elevation M: | 90 |
| Population Total: | 72 |
| Population As Of: | 2001 |
| Postal Code: | 56035 |
| Area Code: | (+39) 0587 |
San Ruffino is a village in Tuscany, central Italy, administratively a frazione of the comune of Casciana Terme Lari, province of Pisa. At the time of the 2001 census its population was 72.[1]
San Ruffino is about 35 km from Pisa and 4 km from Lari.